Molecular detection of Leptospira spp. in small wild rodents from rural areas of São Paulo State, Brazil

BACKGROUND: Leptospirosis represents a One Health issue, affecting humans and animals. This study investigated pathogenic leptospires in small wild rodents in São Paulo, Brazil. METHODS: Kidney samples from 164 rodents underwent qPCR testing, targeting pathogenic Leptospira spp. RESULTS: Thirty-five...

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Autores principales: da Silva, Evelyn Cristine, Fornazari, Felipe, Antunes, João Marcelo Azevedo de Paula, Demoner, Larissa de Castro, de Oliveira, Lucia Helena O’Dwyer, Peres, Marina Gea, Megid, Jane, Langoni, Helio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2023
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550089/
https://www.ncbi.nlm.nih.gov/pubmed/37792829
http://dx.doi.org/10.1590/0037-8682-0160-2023
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author da Silva, Evelyn Cristine
Fornazari, Felipe
Antunes, João Marcelo Azevedo de Paula
Demoner, Larissa de Castro
de Oliveira, Lucia Helena O’Dwyer
Peres, Marina Gea
Megid, Jane
Langoni, Helio
author_facet da Silva, Evelyn Cristine
Fornazari, Felipe
Antunes, João Marcelo Azevedo de Paula
Demoner, Larissa de Castro
de Oliveira, Lucia Helena O’Dwyer
Peres, Marina Gea
Megid, Jane
Langoni, Helio
author_sort da Silva, Evelyn Cristine
collection PubMed
description BACKGROUND: Leptospirosis represents a One Health issue, affecting humans and animals. This study investigated pathogenic leptospires in small wild rodents in São Paulo, Brazil. METHODS: Kidney samples from 164 rodents underwent qPCR testing, targeting pathogenic Leptospira spp. RESULTS: Thirty-five animals (21.34%) tested positive, including five rodent species: Akodon montensis (2/21; 9.5%), Necromys lasiurus (1/4; 25%), Oligoryzomys nigripes (24/92; 26.1%), Oligoryzomys flavescens (5/26; 19.2%), and Sooretamys angouya (3/14; 21.4%). Botucatu municipality exhibited the highest prevalence, with 42.5% (20/47) of the animals testing positive. CONCLUSIONS: The presence of Leptospira spp. in wild rodents suggests they may be chronic carriers, contaminating the environment.
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spelling pubmed-105500892023-10-05 Molecular detection of Leptospira spp. in small wild rodents from rural areas of São Paulo State, Brazil da Silva, Evelyn Cristine Fornazari, Felipe Antunes, João Marcelo Azevedo de Paula Demoner, Larissa de Castro de Oliveira, Lucia Helena O’Dwyer Peres, Marina Gea Megid, Jane Langoni, Helio Rev Soc Bras Med Trop Short Communication BACKGROUND: Leptospirosis represents a One Health issue, affecting humans and animals. This study investigated pathogenic leptospires in small wild rodents in São Paulo, Brazil. METHODS: Kidney samples from 164 rodents underwent qPCR testing, targeting pathogenic Leptospira spp. RESULTS: Thirty-five animals (21.34%) tested positive, including five rodent species: Akodon montensis (2/21; 9.5%), Necromys lasiurus (1/4; 25%), Oligoryzomys nigripes (24/92; 26.1%), Oligoryzomys flavescens (5/26; 19.2%), and Sooretamys angouya (3/14; 21.4%). Botucatu municipality exhibited the highest prevalence, with 42.5% (20/47) of the animals testing positive. CONCLUSIONS: The presence of Leptospira spp. in wild rodents suggests they may be chronic carriers, contaminating the environment. Sociedade Brasileira de Medicina Tropical - SBMT 2023-09-22 /pmc/articles/PMC10550089/ /pubmed/37792829 http://dx.doi.org/10.1590/0037-8682-0160-2023 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Short Communication
da Silva, Evelyn Cristine
Fornazari, Felipe
Antunes, João Marcelo Azevedo de Paula
Demoner, Larissa de Castro
de Oliveira, Lucia Helena O’Dwyer
Peres, Marina Gea
Megid, Jane
Langoni, Helio
Molecular detection of Leptospira spp. in small wild rodents from rural areas of São Paulo State, Brazil
title Molecular detection of Leptospira spp. in small wild rodents from rural areas of São Paulo State, Brazil
title_full Molecular detection of Leptospira spp. in small wild rodents from rural areas of São Paulo State, Brazil
title_fullStr Molecular detection of Leptospira spp. in small wild rodents from rural areas of São Paulo State, Brazil
title_full_unstemmed Molecular detection of Leptospira spp. in small wild rodents from rural areas of São Paulo State, Brazil
title_short Molecular detection of Leptospira spp. in small wild rodents from rural areas of São Paulo State, Brazil
title_sort molecular detection of leptospira spp. in small wild rodents from rural areas of são paulo state, brazil
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550089/
https://www.ncbi.nlm.nih.gov/pubmed/37792829
http://dx.doi.org/10.1590/0037-8682-0160-2023
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