Cargando…
Safety and clinical efficacy of an anti-PD-L1 antibody (c4G12) in dogs with advanced malignant tumours
Immune checkpoint inhibitors (ICIs) have been developed for canine tumour treatment, and pilot clinical studies have demonstrated their antitumour efficacy in dogs with oral malignant melanoma (OMM). Although ICIs have been approved for various human malignancies, their clinical benefits in other tu...
Autores principales: | Maekawa, Naoya, Konnai, Satoru, Hosoya, Kenji, Kim, Sangho, Kinoshita, Ryohei, Deguchi, Tatsuya, Owaki, Ryo, Tachibana, Yurika, Yokokawa, Madoka, Takeuchi, Hiroto, Kagawa, Yumiko, Takagi, Satoshi, Ohta, Hiroshi, Kato, Yukinari, Yamamoto, Satoshi, Yamamoto, Keiichi, Suzuki, Yasuhiko, Okagawa, Tomohiro, Murata, Shiro, Ohashi, Kazuhiko |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550157/ https://www.ncbi.nlm.nih.gov/pubmed/37792729 http://dx.doi.org/10.1371/journal.pone.0291727 |
Ejemplares similares
-
Enhanced Systemic Antitumour Immunity by Hypofractionated Radiotherapy and Anti-PD-L1 Therapy in Dogs with Pulmonary Metastatic Oral Malignant Melanoma
por: Deguchi, Tatsuya, et al.
Publicado: (2023) -
PD-L1 immunohistochemistry for canine cancers and clinical benefit of anti-PD-L1 antibody in dogs with pulmonary metastatic oral malignant melanoma
por: Maekawa, Naoya, et al.
Publicado: (2021) -
Exploration of serum biomarkers in dogs with malignant melanoma receiving anti-PD-L1 therapy and potential of COX-2 inhibition for combination therapy
por: Maekawa, Naoya, et al.
Publicado: (2022) -
Canine Transforming Growth Factor-β Receptor 2-Ig: A Potential Candidate Biologic for Melanoma Treatment That Reverses Transforming Growth Factor-β1 Immunosuppression
por: Takeuchi, Hiroto, et al.
Publicado: (2021) -
A canine chimeric monoclonal antibody targeting PD-L1 and its clinical efficacy in canine oral malignant melanoma or undifferentiated sarcoma
por: Maekawa, Naoya, et al.
Publicado: (2017)