Apollo-NADP(+) reveals in vivo adaptation of NADPH/NADP(+) metabolism in electrically activated pancreatic β cells

Several genetically encoded sensors have been developed to study live cell NADPH/NADP(+) dynamics, but their use has been predominantly in vitro. Here, we developed an in vivo assay using the Apollo-NADP(+) sensor and microfluidic devices to measure endogenous NADPH/NADP(+) dynamics in the pancreati...

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Detalles Bibliográficos
Autores principales: Bui, Cindy V., Boswell, Curtis W., Ciruna, Brian, Rocheleau, Jonathan V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550227/
https://www.ncbi.nlm.nih.gov/pubmed/37792934
http://dx.doi.org/10.1126/sciadv.adi8317

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