Human cytomegalovirus UL36 inhibits IRF3-dependent immune signaling to counterbalance its immunoenhancement as apoptotic inhibitor

Apoptotic inhibition and immune evasion have particular importance to efficient viral infection, while a dilemma often faced by viruses is that inhibiting apoptosis can up-regulate antiviral immune signaling. Herein, we uncovered that in addition to inhibiting caspase-8/extrinsic apoptosis, human cy...

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Detalles Bibliográficos
Autores principales: Ren, Yujie, Wang, An, Zhang, Bowen, Ji, Wenting, Zhu, Xiao-Xu, Lou, Jing, Huang, Muhan, Qiu, Yang, Zhou, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550242/
https://www.ncbi.nlm.nih.gov/pubmed/37792941
http://dx.doi.org/10.1126/sciadv.adi6586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550242/
https://www.ncbi.nlm.nih.gov/pubmed/37792941
http://dx.doi.org/10.1126/sciadv.adi6586

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