A Case of Antipsychiatry Polypill Overdose (200 Tablets) Successfully Treated With Hemodialysis: A Serious Encounter

Polypharmacy refers to using and consuming multiple drugs as part of the treatment for a disease or disorder. Polypharmacy can lead to an increase in the number of drug overdose emergencies. Age-related metabolic changes and reduced drug clearance in older adults can result in severe drug reactions...

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Detalles Bibliográficos
Autores principales: Gemnani, Rinkle, Saboo, Keyur, Deolikar, Vinit, Kumar, Sunil, Acharya, Sourya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Emergency Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550259/
https://www.ncbi.nlm.nih.gov/pubmed/37799240
http://dx.doi.org/10.7759/cureus.44664
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author Gemnani, Rinkle
Saboo, Keyur
Deolikar, Vinit
Kumar, Sunil
Acharya, Sourya
author_facet Gemnani, Rinkle
Saboo, Keyur
Deolikar, Vinit
Kumar, Sunil
Acharya, Sourya
author_sort Gemnani, Rinkle
collection PubMed
description Polypharmacy refers to using and consuming multiple drugs as part of the treatment for a disease or disorder. Polypharmacy can lead to an increase in the number of drug overdose emergencies. Age-related metabolic changes and reduced drug clearance in older adults can result in severe drug reactions and other clinical consequences, which can sometimes be fatal, raising concerns about the safety of polypharmacy. We discuss a case of a 50-year-old female who presented to us in a drowsy state after an antipsychiatry (antipsychotic and antidepressant) polypill overdose with 200 tablets and was successfully treated with hemodialysis. This case report highlights that prompt treatment initiation based on the patient's clinical status and drug serum levels is crucial to achieving the best outcomes.
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spelling pubmed-105502592023-10-05 A Case of Antipsychiatry Polypill Overdose (200 Tablets) Successfully Treated With Hemodialysis: A Serious Encounter Gemnani, Rinkle Saboo, Keyur Deolikar, Vinit Kumar, Sunil Acharya, Sourya Cureus Emergency Medicine Polypharmacy refers to using and consuming multiple drugs as part of the treatment for a disease or disorder. Polypharmacy can lead to an increase in the number of drug overdose emergencies. Age-related metabolic changes and reduced drug clearance in older adults can result in severe drug reactions and other clinical consequences, which can sometimes be fatal, raising concerns about the safety of polypharmacy. We discuss a case of a 50-year-old female who presented to us in a drowsy state after an antipsychiatry (antipsychotic and antidepressant) polypill overdose with 200 tablets and was successfully treated with hemodialysis. This case report highlights that prompt treatment initiation based on the patient's clinical status and drug serum levels is crucial to achieving the best outcomes. Cureus 2023-09-04 /pmc/articles/PMC10550259/ /pubmed/37799240 http://dx.doi.org/10.7759/cureus.44664 Text en Copyright © 2023, Gemnani et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Emergency Medicine
Gemnani, Rinkle
Saboo, Keyur
Deolikar, Vinit
Kumar, Sunil
Acharya, Sourya
A Case of Antipsychiatry Polypill Overdose (200 Tablets) Successfully Treated With Hemodialysis: A Serious Encounter
title A Case of Antipsychiatry Polypill Overdose (200 Tablets) Successfully Treated With Hemodialysis: A Serious Encounter
title_full A Case of Antipsychiatry Polypill Overdose (200 Tablets) Successfully Treated With Hemodialysis: A Serious Encounter
title_fullStr A Case of Antipsychiatry Polypill Overdose (200 Tablets) Successfully Treated With Hemodialysis: A Serious Encounter
title_full_unstemmed A Case of Antipsychiatry Polypill Overdose (200 Tablets) Successfully Treated With Hemodialysis: A Serious Encounter
title_short A Case of Antipsychiatry Polypill Overdose (200 Tablets) Successfully Treated With Hemodialysis: A Serious Encounter
title_sort case of antipsychiatry polypill overdose (200 tablets) successfully treated with hemodialysis: a serious encounter
topic Emergency Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550259/
https://www.ncbi.nlm.nih.gov/pubmed/37799240
http://dx.doi.org/10.7759/cureus.44664
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