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Atypical peripheral actin band formation via overactivation of RhoA and nonmuscle myosin II in mitofusin 2-deficient cells

Cell spreading and migration play central roles in many physiological and pathophysiological processes. We have previously shown that MFN2 regulates the migration of human neutrophil-like cells via suppressing Rac activation. Here, we show that in mouse embryonic fibroblasts, MFN2 suppresses RhoA ac...

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Detalles Bibliográficos
Autores principales: Wang, Yueyang, Troughton, Lee D, Xu, Fan, Chatterjee, Aritra, Ding, Chang, Zhao, Han, Cifuentes, Laura P, Wagner, Ryan B, Wang, Tianqi, Tan, Shelly, Chen, Jingjuan, Li, Linlin, Umulis, David, Kuang, Shihuan, Suter, Daniel M, Yuan, Chongli, Chan, Deva, Huang, Fang, Oakes, Patrick W, Deng, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550287/
https://www.ncbi.nlm.nih.gov/pubmed/37724949
http://dx.doi.org/10.7554/eLife.88828