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Clusters of acidic and hydrophobic residues can predict acidic transcriptional activation domains from protein sequence

Transcription factors activate gene expression in development, homeostasis, and stress with DNA binding domains and activation domains. Although there exist excellent computational models for predicting DNA binding domains from protein sequence, models for predicting activation domains from protein...

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Detalles Bibliográficos
Autores principales: Kotha, Sanjana R, Staller, Max Valentín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550315/
https://www.ncbi.nlm.nih.gov/pubmed/37462277
http://dx.doi.org/10.1093/genetics/iyad131

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