Genetic mapping of the p47 (L.3.2) mutation in Drosophila melanogaster

An EMS-based forward genetic screen was conducted in an apoptotic null background to identify genetic aberrations that contribute to regulation of cell growth in Drosophila melanogaster . The current work maps the genomic location of one of the identified mutants, L.3.2 . Genetic crosses conducted t...

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Detalles Bibliográficos
Autores principales: Cordes, Chloe N, Gouge, Melissa M., Morgan, Hannah, Porter, Carah, Siders, Jamie, Bacab, Erica, Barin, Briana, Becerra, ixel A., Castillo, Jose, Church, Jared, Condo-Hicks, Shaunacee, Conroy, Kattleya J, Curbelo-Navarro, Isbel, DePrest, Benjamin J., Eady, Adrienne, Edmead, TyMahni, Farouk, Verena, Flores-Torres, Angelica, Girmai, Michael, Gutierrez Navarro, Cynthia I., Guzman, Stan, Harris, Alexis B, Healy, Karin, Jaafar, Alina, Khadr, Abraham, Kiboi, Melissa N, Korte, Stephanie N, Lopez, Celia, Mahdi, Hyder, Mendoza Avalos, Jennifer, Miranda, Kathy, Patel, Dipti, Patel, Rishi, Pechulis, Sydney, Plachta, Victoria, Rhodes, Kamryn, Sandoval, Andrea M, Thomas, Caila, Valadez-Mendoza, Joselyn A., Vora, Hannah, Yousif, Jonathan, Bieser, Kayla L, Kagey, Jacob D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2023
Materias:
New Finding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550376/
https://www.ncbi.nlm.nih.gov/pubmed/37799208
http://dx.doi.org/10.17912/micropub.biology.000783
Descripción
Sumario:An EMS-based forward genetic screen was conducted in an apoptotic null background to identify genetic aberrations that contribute to regulation of cell growth in Drosophila melanogaster . The current work maps the genomic location of one of the identified mutants, L.3.2 . Genetic crosses conducted through the Fly-CURE consortium determined that the gene locus for the L.3.2 mutation is p47 on chromosome 2R.

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