Time course study of Paenarthrobacter nicotinovorans secondary metabolite toxicity profile

In previous studies , Paenarthrobacter nicotinovorans was isolated and screened for antimicrobial activity. Further, secondary metabolites were isolated and screened for antimicrobial activity and cytotoxicity in vitro . The current study determines if increased exposure of Hela cells to the seconda...

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Autores principales: Kakol, Justyna, Vang, Mainor, Sausen, Drew, Steeno, Tracey, Kolokithas, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2023
Materias:
Findings Previously Not Shown
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550379/
https://www.ncbi.nlm.nih.gov/pubmed/37799202
http://dx.doi.org/10.17912/micropub.biology.000922
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author Kakol, Justyna
Vang, Mainor
Sausen, Drew
Steeno, Tracey
Kolokithas, Angelo
author_facet Kakol, Justyna
Vang, Mainor
Sausen, Drew
Steeno, Tracey
Kolokithas, Angelo
author_sort Kakol, Justyna
collection PubMed
description In previous studies , Paenarthrobacter nicotinovorans was isolated and screened for antimicrobial activity. Further, secondary metabolites were isolated and screened for antimicrobial activity and cytotoxicity in vitro . The current study determines if increased exposure of Hela cells to the secondary metabolites over time increases the cytotoxicity. The results show no detectable increase of cytotoxicity in HeLa cells.
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spelling pubmed-105503792023-10-05 Time course study of Paenarthrobacter nicotinovorans secondary metabolite toxicity profile Kakol, Justyna Vang, Mainor Sausen, Drew Steeno, Tracey Kolokithas, Angelo MicroPubl Biol Findings Previously Not Shown In previous studies , Paenarthrobacter nicotinovorans was isolated and screened for antimicrobial activity. Further, secondary metabolites were isolated and screened for antimicrobial activity and cytotoxicity in vitro . The current study determines if increased exposure of Hela cells to the secondary metabolites over time increases the cytotoxicity. The results show no detectable increase of cytotoxicity in HeLa cells. Caltech Library 2023-09-19 /pmc/articles/PMC10550379/ /pubmed/37799202 http://dx.doi.org/10.17912/micropub.biology.000922 Text en Copyright: © 2023 by the authors https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Findings Previously Not Shown
Kakol, Justyna
Vang, Mainor
Sausen, Drew
Steeno, Tracey
Kolokithas, Angelo
Time course study of Paenarthrobacter nicotinovorans secondary metabolite toxicity profile
title Time course study of Paenarthrobacter nicotinovorans secondary metabolite toxicity profile
title_full Time course study of Paenarthrobacter nicotinovorans secondary metabolite toxicity profile
title_fullStr Time course study of Paenarthrobacter nicotinovorans secondary metabolite toxicity profile
title_full_unstemmed Time course study of Paenarthrobacter nicotinovorans secondary metabolite toxicity profile
title_short Time course study of Paenarthrobacter nicotinovorans secondary metabolite toxicity profile
title_sort time course study of paenarthrobacter nicotinovorans secondary metabolite toxicity profile
topic Findings Previously Not Shown
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550379/
https://www.ncbi.nlm.nih.gov/pubmed/37799202
http://dx.doi.org/10.17912/micropub.biology.000922
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