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Central Mucoepidermoid Carcinoma Radiographically Mimicking an Odontogenic Lesion
Central mucoepidermoid carcinoma (CMEC) is a rare pathological entity with only a few case reports in the literature. The present case reported an uncommon occurrence of CMEC mimicking an odontogenic lesion in a young patient. A 17-year-old female patient sought dental care due to a slight swelling...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550484/ https://www.ncbi.nlm.nih.gov/pubmed/37799173 http://dx.doi.org/10.1155/2023/5714099 |
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author | Teixeira, Lucas Novaes Perez, Erick Gomes Rosa, Ana Cláudia Garcia Lima, Sandro Régis Rodrigues Soares, Mariana Quirino Silveira Passador-Santos, Fabricio de Araújo, Vera Cavalcanti Soares, Andresa Borges |
author_facet | Teixeira, Lucas Novaes Perez, Erick Gomes Rosa, Ana Cláudia Garcia Lima, Sandro Régis Rodrigues Soares, Mariana Quirino Silveira Passador-Santos, Fabricio de Araújo, Vera Cavalcanti Soares, Andresa Borges |
author_sort | Teixeira, Lucas Novaes |
collection | PubMed |
description | Central mucoepidermoid carcinoma (CMEC) is a rare pathological entity with only a few case reports in the literature. The present case reported an uncommon occurrence of CMEC mimicking an odontogenic lesion in a young patient. A 17-year-old female patient sought dental care due to a slight swelling located in the posterior region of the mandible on the left side. Radiographic exams revealed an osteolytic lesion with defined limits in relation to proximity to the pericoronal follicle of tooth #38. The clinical and radiographic diagnostic hypothesis was an odontogenic lesion. Histological sections showed the presence of a neoplasm of glandular origin, not encapsulated, with a predominantly cystic growth pattern. The neoplasm consisted of mucous, intermediate, and squamous cells. In the immunohistochemical staining, the neoplastic cells were positive for cytokeratin 7. Mucous cells were positive for PAS with diastase digestion. The final diagnosis consisted of mucoepidermoid carcinoma. The tumor was removed surgically, and the patient has shown no signs of relapse nor recurrence. In conclusion, CMEC may mimic radiographic features of various pathologies, but despite its rarity, clinicians and oral radiologists should consider CMEC as a diagnostic hypothesis for jaw lesions. |
format | Online Article Text |
id | pubmed-10550484 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-105504842023-10-05 Central Mucoepidermoid Carcinoma Radiographically Mimicking an Odontogenic Lesion Teixeira, Lucas Novaes Perez, Erick Gomes Rosa, Ana Cláudia Garcia Lima, Sandro Régis Rodrigues Soares, Mariana Quirino Silveira Passador-Santos, Fabricio de Araújo, Vera Cavalcanti Soares, Andresa Borges Case Rep Dent Case Report Central mucoepidermoid carcinoma (CMEC) is a rare pathological entity with only a few case reports in the literature. The present case reported an uncommon occurrence of CMEC mimicking an odontogenic lesion in a young patient. A 17-year-old female patient sought dental care due to a slight swelling located in the posterior region of the mandible on the left side. Radiographic exams revealed an osteolytic lesion with defined limits in relation to proximity to the pericoronal follicle of tooth #38. The clinical and radiographic diagnostic hypothesis was an odontogenic lesion. Histological sections showed the presence of a neoplasm of glandular origin, not encapsulated, with a predominantly cystic growth pattern. The neoplasm consisted of mucous, intermediate, and squamous cells. In the immunohistochemical staining, the neoplastic cells were positive for cytokeratin 7. Mucous cells were positive for PAS with diastase digestion. The final diagnosis consisted of mucoepidermoid carcinoma. The tumor was removed surgically, and the patient has shown no signs of relapse nor recurrence. In conclusion, CMEC may mimic radiographic features of various pathologies, but despite its rarity, clinicians and oral radiologists should consider CMEC as a diagnostic hypothesis for jaw lesions. Hindawi 2023-09-27 /pmc/articles/PMC10550484/ /pubmed/37799173 http://dx.doi.org/10.1155/2023/5714099 Text en Copyright © 2023 Lucas Novaes Teixeira et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Teixeira, Lucas Novaes Perez, Erick Gomes Rosa, Ana Cláudia Garcia Lima, Sandro Régis Rodrigues Soares, Mariana Quirino Silveira Passador-Santos, Fabricio de Araújo, Vera Cavalcanti Soares, Andresa Borges Central Mucoepidermoid Carcinoma Radiographically Mimicking an Odontogenic Lesion |
title | Central Mucoepidermoid Carcinoma Radiographically Mimicking an Odontogenic Lesion |
title_full | Central Mucoepidermoid Carcinoma Radiographically Mimicking an Odontogenic Lesion |
title_fullStr | Central Mucoepidermoid Carcinoma Radiographically Mimicking an Odontogenic Lesion |
title_full_unstemmed | Central Mucoepidermoid Carcinoma Radiographically Mimicking an Odontogenic Lesion |
title_short | Central Mucoepidermoid Carcinoma Radiographically Mimicking an Odontogenic Lesion |
title_sort | central mucoepidermoid carcinoma radiographically mimicking an odontogenic lesion |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550484/ https://www.ncbi.nlm.nih.gov/pubmed/37799173 http://dx.doi.org/10.1155/2023/5714099 |
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