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Targeting BMI‐1 to deplete antibody‐secreting cells in autoimmunity

OBJECTIVES: B cells drive the production of autoreactive antibody‐secreting cells (ASCs) in autoimmune diseases such as Systemic Lupus Erythematosus (SLE) and Sjögren's syndrome, causing long‐term organ damage. Current treatments for antibody‐mediated autoimmune diseases target B cells or broad...

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Detalles Bibliográficos
Autores principales: Polmear, Jack, Hailes, Lauren, Olshansky, Moshe, Rischmueller, Maureen, L'Estrange‐Stranieri, Elan, Fletcher, Anne L, Hibbs, Margaret L, Bryant, Vanessa L, Good‐Jacobson, Kim L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550498/
https://www.ncbi.nlm.nih.gov/pubmed/37799772
http://dx.doi.org/10.1002/cti2.1470

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