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Distinct HLA associations with autoantibody-defined subgroups in idiopathic inflammatory myopathies

BACKGROUND: In patients with idiopathic inflammatory myopathies (IIM), autoantibodies are associated with specific clinical phenotypes suggesting a pathogenic role of adaptive immunity. We explored if autoantibody profiles are associated with specific HLA genetic variants and clinical manifestations...

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Detalles Bibliográficos
Autores principales: Leclair, Valérie, Galindo-Feria, Angeles S., Rothwell, Simon, Kryštůfková, Olga, Zargar, Sepehr Sarrafzadeh, Mann, Herman, Diederichsen, Louise Pyndt, Andersson, Helena, Klein, Martin, Tansley, Sarah, Rönnblom, Lars, Lindblad-Toh, Kerstin, Syvänen, Ann-Christine, Wahren-Herlenius, Marie, Sandling, Johanna K., McHugh, Neil, Lamb, Janine A., Vencovský, Jiri, Chinoy, Hector, Holmqvist, Marie, Bianchi, Matteo, Padyukov, Leonid, Lundberg, Ingrid E., Diaz-Gallo, Lina-Marcela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550566/
https://www.ncbi.nlm.nih.gov/pubmed/37769433
http://dx.doi.org/10.1016/j.ebiom.2023.104804

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