Biological informed graph neural network for tumor mutation burden prediction and immunotherapy-related pathway analysis in gastric cancer

Tumor mutation burden (TMB) has emerged as an essential biomarker for assessing the efficacy of cancer immunotherapy. However, due to the inherent complexity of tumors, TMB is not always correlated with the responsiveness of immune checkpoint inhibitors (ICIs). Thus, refining the interpretation and...

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Detalles Bibliográficos
Autores principales: Liu, Chuwei, Wan, Arabella H., Liang, Heng, Sun, Lei, Li, Jiarui, Yang, Ranran, Li, Qinghai, Wu, Ruibo, Hu, Kunhua, Yang, Yuedong, Cai, Shirong, Wan, Guohui, He, Weiling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550590/
https://www.ncbi.nlm.nih.gov/pubmed/37810279
http://dx.doi.org/10.1016/j.csbj.2023.09.021

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