Glycolysis maintains AMPK activation in sorafenib-induced Warburg effect

Hepatocellular carcinoma (HCC) is the second deadly cancer in the world and still lacks curative treatment. Aerobic glycolysis, or Warburg effect, is a major resistance mechanism induced by first-line treatment of HCC, sorafenib, and is regulated by the master regulator of metabolism, AMPK. Activati...

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Detalles Bibliográficos
Autores principales: Guo, Sijia, Zhang, Chenhao, Zeng, Haiou, Xia, Yantao, Weng, Chenghao, Deng, Yichen, Wang, Luda, Wang, Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550717/
https://www.ncbi.nlm.nih.gov/pubmed/37696356
http://dx.doi.org/10.1016/j.molmet.2023.101796

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