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Spatial downregulation of CD74 signatures may drive invasive component development in part-solid lung adenocarcinoma
Pulmonary nodules with part-solid imaging features manifest during the progression from preinvasive to invasive lung adenocarcinoma. To define the spatial composition and evolutionary trajectories of early-stage lung adenocarcinoma, we combined spatial transcriptomics (ST) and pathological annotatio...
Autores principales: | Zhang, Jia-Tao, Zhang, Juan, Wang, Song-Rong, Yan, Li-Xu, Qin, Jing, Yin, Kai, Chu, Xiang-Peng, Wang, Meng-Min, Hong, Hui-Zhao, Lv, Zhi-Yi, Dong, Song, Jiang, Ben-Yuan, Zhang, Xu-Chao, Liu, Xiang, Zhou, Qing, Wu, Yi-Long, Zhong, Wen-Zhao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550719/ https://www.ncbi.nlm.nih.gov/pubmed/37810252 http://dx.doi.org/10.1016/j.isci.2023.107699 |
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