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Hyperuricemia remodels the serum proteome toward a higher inflammatory state
Gout is an autoinflammatory disease triggered by a complex innate immune response to MSU crystals and inflammatory triggers. While hyperuricemia is an obligatory risk factor for the development of gout, the majority of individuals with hyperuricemia never develop gout but have an increased risk of d...
Autores principales: | Cabău, Georgiana, Gaal, Orsolya, Badii, Medeea, Nica, Valentin, Mirea, Andreea-Manuela, Hotea, Ioana, Pamfil, Cristina, Popp, Radu A., Netea, Mihai G., Rednic, Simona, Crișan, Tania O., Joosten, Leo A.B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550725/ https://www.ncbi.nlm.nih.gov/pubmed/37810213 http://dx.doi.org/10.1016/j.isci.2023.107909 |
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