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Melatonin-loaded self-healing hydrogel targets mitochondrial energy metabolism and promotes annulus fibrosus regeneration

Intervertebral disc (IVD) herniation is a major cause of chronic low back pain and disability. The current nucleus pulposus (NP) discectomy effectively relieves pain symptoms, but the annulus fibrosus (AF) defects are left unrepaired. Tissue engineering approaches show promise in treating AF injury...

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Detalles Bibliográficos
Autores principales:	Hu, Xiayu, Tian, Xin, Yang, Chunju, Ling, Feng, Liu, Hao, Zhu, Xuesong, Pei, Ming, Yang, Huilin, Liu, Tao, Xu, Yong, He, Fan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Full Length Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550778/ https://www.ncbi.nlm.nih.gov/pubmed/37810753 http://dx.doi.org/10.1016/j.mtbio.2023.100811

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