Testing the cognitive effects of tadalafil. Neuropsychological secondary outcomes from the PASTIS trial

Cerebral small vessel disease (SVD) is a major cause of cognitive impairment in older people. As secondary endpoints in a phase-2 randomised clinical trial, we tested the effects of single administration of a widely-used PDE5 inhibitor, tadalafil, on cognitive performance in older people with SVD. I...

Descripción completa

Detalles Bibliográficos
Autores principales: Pauls, Mathilde MH, Fish, Jessica, Binnie, Lauren R, Benjamin, Philip, Betteridge, Shai, Clarke, Brian, Dhillon, Mohani-Preet K, Ghatala, Rita, Hainsworth, Fearghal AH, Howe, Franklyn A, Khan, Usman, Kruuse, Christina, Madigan, Jeremy B, Moynihan, Barry, Patel, Bhavini, Pereira, Anthony C, Rostrup, Egill, Shtaya, Anan BY, Spilling, Catherine A, Trippier, Sarah, Williams, Rebecca, Young, Robin, Barrick, Thomas R, Isaacs, Jeremy D, Hainsworth, Atticus H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550803/
https://www.ncbi.nlm.nih.gov/pubmed/37811523
http://dx.doi.org/10.1016/j.cccb.2023.100187

Ejemplares similares

Ejemplares similares