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Decoding the role of angiopoietin-like protein 4/8 complex–mediated plasmin generation in the regulation of LPL activity

After feeding, adipose tissue lipoprotein lipase (LPL) activity should be maximized, therefore the potent LPL-inhibitory activity of angiopoietin-like protein 4 (ANGPTL4) must be blocked by ANGPTL8 through formation of ANGPTL4/8 complexes. ANGPTL4/8 tightly binds and protects LPL but also partially...

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Detalles Bibliográficos
Autores principales:	Chen, Yan Q., Zhen, Eugene Y., Russell, Anna M., Ehsani, Mariam, Siegel, Robert W., Qian, Yuewei, Konrad, Robert J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550811/ https://www.ncbi.nlm.nih.gov/pubmed/37666362 http://dx.doi.org/10.1016/j.jlr.2023.100441

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