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Cryo-EM structures reveal native GABA(A) receptor assemblies and pharmacology
Type A γ-aminobutyric acid receptors (GABA(A)Rs) are the principal inhibitory receptors in the brain and the target of a wide range of clinical agents, including anaesthetics, sedatives, hypnotics and antidepressants(1–3). However, our understanding of GABA(A)R pharmacology has been hindered by the...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550821/ https://www.ncbi.nlm.nih.gov/pubmed/37730991 http://dx.doi.org/10.1038/s41586-023-06556-w |