High-resolution landscape of an antibiotic binding site

Antibiotic binding sites are located in important domains of essential enzymes and have been extensively studied in the context of resistance mutations; however, their study is limited by positive selection. Using multiplex genome engineering(1) to overcome this constraint, we generate and character...

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Detalles Bibliográficos
Autores principales: Yang, Kevin B., Cameranesi, Maria, Gowder, Manjunath, Martinez, Criseyda, Shamovsky, Yosef, Epshtein, Vitaliy, Hao, Zhitai, Nguyen, Thao, Nirenstein, Eric, Shamovsky, Ilya, Rasouly, Aviram, Nudler, Evgeny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550828/
https://www.ncbi.nlm.nih.gov/pubmed/37648864
http://dx.doi.org/10.1038/s41586-023-06495-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550828/
https://www.ncbi.nlm.nih.gov/pubmed/37648864
http://dx.doi.org/10.1038/s41586-023-06495-6

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