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High-resolution landscape of an antibiotic binding site
Antibiotic binding sites are located in important domains of essential enzymes and have been extensively studied in the context of resistance mutations; however, their study is limited by positive selection. Using multiplex genome engineering(1) to overcome this constraint, we generate and character...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550828/ https://www.ncbi.nlm.nih.gov/pubmed/37648864 http://dx.doi.org/10.1038/s41586-023-06495-6 |