Evaluating genomic polygenic risk scores for childhood acute lymphoblastic leukemia in Latinos

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The utility of polygenic risk score (PRS) models has not been comprehensively evaluated for childhood acute lymphoblastic leukemia (ALL), the most common type of cancer in children. Previous PRS models for ALL were based on significant loci observed in genome-wide association studies (GWASs), even t...

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Detalles Bibliográficos
Autores principales: Jeon, Soyoung, Lo, Ying Chu, Morimoto, Libby M., Metayer, Catherine, Ma, Xiaomei, Wiemels, Joseph L., de Smith, Adam J., Chiang, Charleston W.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550840/
https://www.ncbi.nlm.nih.gov/pubmed/37710962
http://dx.doi.org/10.1016/j.xhgg.2023.100239
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