Sec22b regulates phagosome maturation by promoting ORP8-mediated lipid exchange at endoplasmic reticulum-phagosome contact sites

Phagosome maturation is critical for immune defense, defining whether ingested material is destroyed or converted into antigens. Sec22b regulates phagosome maturation, yet how has remained unclear. Here we show Sec22b tethers endoplasmic reticulum-phagosome membrane contact sites (MCS) independently...

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Detalles Bibliográficos
Autores principales: Criado Santos, Nina, Bouvet, Samuel, Cruz Cobo, Maria, Mandavit, Marion, Bermont, Flavien, Castelbou, Cyril, Mansour, Farah, Azam, Maral, Giordano, Francesca, Nunes-Hasler, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550925/
https://www.ncbi.nlm.nih.gov/pubmed/37794132
http://dx.doi.org/10.1038/s42003-023-05382-0

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