Cytoplasmic Endonuclease G promotes nonalcoholic fatty liver disease via mTORC2-AKT-ACLY and endoplasmic reticulum stress

Endonuclease G (ENDOG), a nuclear-encoded mitochondrial intermembrane space protein, is well known to be translocated into the nucleus during apoptosis. Recent studies have shown that ENDOG might enter the mitochondrial matrix to regulate mitochondrial genome cleavage and replication. However, littl...

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Detalles Bibliográficos
Autores principales: Wang, Wenjun, Tan, Junyang, Liu, Xiaomin, Guo, Wenqi, Li, Mengmeng, Liu, Xinjie, Liu, Yanyan, Dai, Wenyu, Hu, Liubing, Wang, Yimin, Lu, Qiuxia, Lee, Wen Xing, Tang, Hong-Wen, Zhou, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550995/
https://www.ncbi.nlm.nih.gov/pubmed/37794041
http://dx.doi.org/10.1038/s41467-023-41757-x

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