Nanoparticle display of prefusion coronavirus spike elicits S1-focused cross-reactive antibody response against diverse coronavirus subgenera

Multivalent antigen display is a fast-growing area of interest toward broadly protective vaccines. Current nanoparticle-based vaccine candidates demonstrate the ability to confer antibody-mediated immunity against divergent strains of notably mutable viruses. In coronaviruses, this work is predomina...

Descripción completa

Detalles Bibliográficos
Autores principales: Hutchinson, Geoffrey B., Abiona, Olubukola M., Ziwawo, Cynthia T., Werner, Anne P., Ellis, Daniel, Tsybovsky, Yaroslav, Leist, Sarah R., Palandjian, Charis, West, Ande, Fritch, Ethan J., Wang, Nianshuang, Wrapp, Daniel, Boyoglu-Barnum, Seyhan, Ueda, George, Baker, David, Kanekiyo, Masaru, McLellan, Jason S., Baric, Ralph S., King, Neil P., Graham, Barney S., Corbett-Helaire, Kizzmekia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551005/
https://www.ncbi.nlm.nih.gov/pubmed/37794071
http://dx.doi.org/10.1038/s41467-023-41661-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551005/
https://www.ncbi.nlm.nih.gov/pubmed/37794071
http://dx.doi.org/10.1038/s41467-023-41661-4

Ejemplares similares