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Sestrin2 protects against hypoxic nerve injury by regulating mitophagy through SESN2/AMPK pathway

Hypoxia induced by high altitude can lead to severe neurological dysfunction. Mitophagy is known to play a crucial role in hypoxic nerve injury. However, the regulatory mechanism of mitophagy during this injury remains unclear. Recent studies have highlighted the role of Sestrin2 (SESN2), an evoluti...

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Detalles Bibliográficos
Autores principales: Pan, Cunyao, Ai, Chongyi, Liang, Lanlan, Zhang, Baoyi, Li, Qionglin, Pu, Lingling, Wang, Zirou, Liu, Weili, Chen, Zhaoli, Liu, Hui, Wang, Xinxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551140/
https://www.ncbi.nlm.nih.gov/pubmed/37808523
http://dx.doi.org/10.3389/fmolb.2023.1266243