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Annulation of O-silyl N,O-ketene acetals with alkynes for the synthesis of dihydropyridinones and its application in concise total synthesis of phenanthroindolizidine alkaloids

The formation of N-heterocycles with multiple substituents is important in organic synthesis. Herein, we report a novel method for the construction of functionalized dihydropyridinone rings through the annulation of an amide α-carbon with a tethered alkyne moiety. The reaction of the amide with the...

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Detalles Bibliográficos
Autores principales:	Lee, Seokwoo, Shin, Jae Eui, Yoon, Ran, Yoo, Hanbin, Kim, Sanghee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551152/ https://www.ncbi.nlm.nih.gov/pubmed/37810583 http://dx.doi.org/10.3389/fchem.2023.1267422

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