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Possible mechanisms of treatment for spinal cord injury repair with tanshinone IIA
Tanshinone IIA serves as a coenzyme for certain biochemical reactions, exhibiting various pharmacological effects in the treatment of neurological diseases including spinal cord injury (SCI), however, its working mechanism in the treatment of SCI is not clear. Based on previous research, we believe...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551456/ https://www.ncbi.nlm.nih.gov/pubmed/37808475 http://dx.doi.org/10.3389/fnmol.2023.1277755 |
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author | Jia, Zhiwei Wen, Tianlin Zhang, Yuning |
author_facet | Jia, Zhiwei Wen, Tianlin Zhang, Yuning |
author_sort | Jia, Zhiwei |
collection | PubMed |
description | Tanshinone IIA serves as a coenzyme for certain biochemical reactions, exhibiting various pharmacological effects in the treatment of neurological diseases including spinal cord injury (SCI), however, its working mechanism in the treatment of SCI is not clear. Based on previous research, we believe that tanshinone IIA promotes the survival and repair of nerves after spinal cord injury through its pharmacological effects such as anti-inflammatory, antioxidant, and prevention of cellular apoptosis in the spinal cord. |
format | Online Article Text |
id | pubmed-10551456 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-105514562023-10-06 Possible mechanisms of treatment for spinal cord injury repair with tanshinone IIA Jia, Zhiwei Wen, Tianlin Zhang, Yuning Front Mol Neurosci Molecular Neuroscience Tanshinone IIA serves as a coenzyme for certain biochemical reactions, exhibiting various pharmacological effects in the treatment of neurological diseases including spinal cord injury (SCI), however, its working mechanism in the treatment of SCI is not clear. Based on previous research, we believe that tanshinone IIA promotes the survival and repair of nerves after spinal cord injury through its pharmacological effects such as anti-inflammatory, antioxidant, and prevention of cellular apoptosis in the spinal cord. Frontiers Media S.A. 2023-09-21 /pmc/articles/PMC10551456/ /pubmed/37808475 http://dx.doi.org/10.3389/fnmol.2023.1277755 Text en Copyright © 2023 Jia, Wen and Zhang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Molecular Neuroscience Jia, Zhiwei Wen, Tianlin Zhang, Yuning Possible mechanisms of treatment for spinal cord injury repair with tanshinone IIA |
title | Possible mechanisms of treatment for spinal cord injury repair with tanshinone IIA |
title_full | Possible mechanisms of treatment for spinal cord injury repair with tanshinone IIA |
title_fullStr | Possible mechanisms of treatment for spinal cord injury repair with tanshinone IIA |
title_full_unstemmed | Possible mechanisms of treatment for spinal cord injury repair with tanshinone IIA |
title_short | Possible mechanisms of treatment for spinal cord injury repair with tanshinone IIA |
title_sort | possible mechanisms of treatment for spinal cord injury repair with tanshinone iia |
topic | Molecular Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551456/ https://www.ncbi.nlm.nih.gov/pubmed/37808475 http://dx.doi.org/10.3389/fnmol.2023.1277755 |
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