Metastasis and immunosuppression promoted by mtDNA and PD‐L1 in extracellular vesicles are reversed by WGP β‐glucan in oral squamous cell carcinoma

The suppressive regulatory T cells (Treg) are frequently upregulated in cancer patients. This study aims to demonstrate the hypothesis that arecoline could induce the secretion of mitochondrial (mt) DNA D‐loop and programmed cell death‐ligand 1 (PD‐L1) in extracellular vesicles (EVs), and attenuate...

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Detalles Bibliográficos
Autores principales: Ko, Hui‐Hsin, Peng, Hsin‐Hui, Cheng, An Ning, Chou, Han‐Yi Elizabeth, Hou, Hsin‐Han, Kuo, Wei‐Ting, Liu, Wei‐Wen, Kuo, Mark Yen‐Ping, Lee, Alan Yueh‐Luen, Cheng, Shih‐Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551585/
https://www.ncbi.nlm.nih.gov/pubmed/37525561
http://dx.doi.org/10.1111/cas.15919

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