Single‐cell RNA‐seq reveals a microenvironment and an exhaustion state of T/NK cells in acute myeloid leukemia

Acute myeloid leukemia (AML) is a heterogeneous blood cancer. Effective immunotherapies for AML are hindered by a lack of understanding of the tumor microenvironment (TME). Here, we retrieved published single‐cell RNA sequencing data for 128,688 cells derived from 29 bone marrow aspirates, including...

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Detalles Bibliográficos
Autores principales: Zhang, Zhiyong, Deng, Cong, Zhu, Pei, Yao, Danlin, Shi, Jinlong, Zeng, Tiansheng, Huang, Wenhui, Huang, Zeyong, Wu, Zhihua, Li, Junyi, Xiao, Min, Fu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551605/
https://www.ncbi.nlm.nih.gov/pubmed/37591615
http://dx.doi.org/10.1111/cas.15932

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