Genetic inactivation of essential HSF1 reveals an isolated transcriptional stress response selectively induced by protein misfolding

Heat Shock Factor 1 (Hsf1) in yeast drives the basal transcription of key proteostasis factors and its activity is induced as part of the core heat shock response. Exploring Hsf1 specific functions has been challenging due to the essential nature of the HSF1 gene and the extensive overlap of target...

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Detalles Bibliográficos
Autores principales: Ciccarelli, Michela, Masser, Anna E., Kaimal, Jayasankar Mohanakrishnan, Planells, Jordi, Andréasson, Claes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2023
Materias:
Special Issue on Protein Quality Control
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551698/
https://www.ncbi.nlm.nih.gov/pubmed/37467033
http://dx.doi.org/10.1091/mbc.E23-05-0153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551698/
https://www.ncbi.nlm.nih.gov/pubmed/37467033
http://dx.doi.org/10.1091/mbc.E23-05-0153

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