Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Pneumonia in Patients Treated With Anti-CD20 Monoclonal Antibodies

We report 8 cases of persistent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia in patients previously treated with anti-CD20 monoclonal antibodies. Polymerase chain reaction of nasopharyngeal swabs for SARS-CoV-2 was negative in most cases; viral cell cultures confirmed that...

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Autores principales: Furie, Nadav, Mandelboim, Michal, Zuckerman, Neta, Belkin, Ana, Seluk, Lior, Shafran, Inbal, Mass, Ronen, Levy, Liran, Chatterji, Sumit, Baltaxe, Erik, Peled, Michael, Shulimzon, Tiberiu, Avigdor, Abraham, Amit, Sharon, Onn, Amir, Marom, Edith M, Rahav, Galia, Segel, Michael J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551847/
https://www.ncbi.nlm.nih.gov/pubmed/37808896
http://dx.doi.org/10.1093/ofid/ofad464
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author Furie, Nadav
Mandelboim, Michal
Zuckerman, Neta
Belkin, Ana
Seluk, Lior
Shafran, Inbal
Mass, Ronen
Levy, Liran
Chatterji, Sumit
Baltaxe, Erik
Peled, Michael
Shulimzon, Tiberiu
Avigdor, Abraham
Amit, Sharon
Onn, Amir
Marom, Edith M
Rahav, Galia
Segel, Michael J
author_facet Furie, Nadav
Mandelboim, Michal
Zuckerman, Neta
Belkin, Ana
Seluk, Lior
Shafran, Inbal
Mass, Ronen
Levy, Liran
Chatterji, Sumit
Baltaxe, Erik
Peled, Michael
Shulimzon, Tiberiu
Avigdor, Abraham
Amit, Sharon
Onn, Amir
Marom, Edith M
Rahav, Galia
Segel, Michael J
author_sort Furie, Nadav
collection PubMed
description We report 8 cases of persistent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia in patients previously treated with anti-CD20 monoclonal antibodies. Polymerase chain reaction of nasopharyngeal swabs for SARS-CoV-2 was negative in most cases; viral cell cultures confirmed that viable SARS-Co-2 virus was present. Four patients were treated with anti-SARS-CoV-2 hyperimmune globulins with rapid resolution of disease.
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spelling pubmed-105518472023-10-06 Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Pneumonia in Patients Treated With Anti-CD20 Monoclonal Antibodies Furie, Nadav Mandelboim, Michal Zuckerman, Neta Belkin, Ana Seluk, Lior Shafran, Inbal Mass, Ronen Levy, Liran Chatterji, Sumit Baltaxe, Erik Peled, Michael Shulimzon, Tiberiu Avigdor, Abraham Amit, Sharon Onn, Amir Marom, Edith M Rahav, Galia Segel, Michael J Open Forum Infect Dis Brief Report We report 8 cases of persistent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia in patients previously treated with anti-CD20 monoclonal antibodies. Polymerase chain reaction of nasopharyngeal swabs for SARS-CoV-2 was negative in most cases; viral cell cultures confirmed that viable SARS-Co-2 virus was present. Four patients were treated with anti-SARS-CoV-2 hyperimmune globulins with rapid resolution of disease. Oxford University Press 2023-09-15 /pmc/articles/PMC10551847/ /pubmed/37808896 http://dx.doi.org/10.1093/ofid/ofad464 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Report
Furie, Nadav
Mandelboim, Michal
Zuckerman, Neta
Belkin, Ana
Seluk, Lior
Shafran, Inbal
Mass, Ronen
Levy, Liran
Chatterji, Sumit
Baltaxe, Erik
Peled, Michael
Shulimzon, Tiberiu
Avigdor, Abraham
Amit, Sharon
Onn, Amir
Marom, Edith M
Rahav, Galia
Segel, Michael J
Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Pneumonia in Patients Treated With Anti-CD20 Monoclonal Antibodies
title Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Pneumonia in Patients Treated With Anti-CD20 Monoclonal Antibodies
title_full Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Pneumonia in Patients Treated With Anti-CD20 Monoclonal Antibodies
title_fullStr Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Pneumonia in Patients Treated With Anti-CD20 Monoclonal Antibodies
title_full_unstemmed Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Pneumonia in Patients Treated With Anti-CD20 Monoclonal Antibodies
title_short Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Pneumonia in Patients Treated With Anti-CD20 Monoclonal Antibodies
title_sort persistent severe acute respiratory syndrome coronavirus 2 pneumonia in patients treated with anti-cd20 monoclonal antibodies
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551847/
https://www.ncbi.nlm.nih.gov/pubmed/37808896
http://dx.doi.org/10.1093/ofid/ofad464
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