Multiple mechanisms of self-association of chemokine receptors CXCR4 and CCR5 demonstrated by deep mutagenesis

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Chemokine receptors are members of the rhodopsin-like class A GPCRs whose signaling through G proteins drives the directional movement of cells in response to a chemokine gradient. Chemokine receptors CXCR4 and CCR5 have been extensively studied due to their roles in leukocyte development and inflam...

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Detalles Bibliográficos
Autores principales: Gill, Kevin S., Mehta, Kritika, Heredia, Jeremiah D., Krishnamurthy, Vishnu V., Zhang, Kai, Procko, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551899/
https://www.ncbi.nlm.nih.gov/pubmed/37690681
http://dx.doi.org/10.1016/j.jbc.2023.105229

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