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Discovery of a glucocorticoid receptor (GR) activity signature correlates with immune cell infiltration in adrenocortical carcinoma

BACKGROUND: Adrenocortical carcinoma (ACC) is a rare and highly aggressive endocrine malignancy, of which >40% present with glucocorticoid excess. Glucocorticoids and glucocorticoid receptor (GR) signaling have long been thought to suppress immunity and promote tumor progression by acting on immu...

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Detalles Bibliográficos
Autores principales:	Wu, Kan, Liu, Zhihong, Liang, Jiayu, Zhu, Yuchun, Wang, Xianding, Li, Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Immunotherapy Biomarkers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551943/ https://www.ncbi.nlm.nih.gov/pubmed/37793855 http://dx.doi.org/10.1136/jitc-2023-007528

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