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Kynurenic acid inhibits macrophage pyroptosis by suppressing ROS production via activation of the NRF2 pathway

Macrophage pyroptosis and related inflammatory responses play an important role in periodontitis. Kynurenic acid (KA) is hypothesized to have anti-inflammatory potential, but whether KA can inhibit macrophage pyroptosis and the underlying mechanisms remain unclear. Lipopolysaccharide (LPS) was used...

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Detalles Bibliográficos
Autores principales:	Gao, Yuwei, Guo, Xiaohui, Zhou, Yunpeng, Du, Jie, Lu, Chengbo, Zhang, Lei, Sun, Siyuan, Wang, Shengfang, Li, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552067/ https://www.ncbi.nlm.nih.gov/pubmed/37772394 http://dx.doi.org/10.3892/mmr.2023.13098

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