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Impaired cAMP processivity by phosphodiesterase-protein kinase A complexes in acrodysostosis

Acrodysostosis represents a group of rare genetic disorders characterized by defective skeletal development and is often accompanied by intellectual disabilities. Mutations in the 3′5′cyclic AMP (cAMP)-dependent protein kinase (PKA) type I regulatory subunit isoform α (RIα) and phosphodiesterase (PD...

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Detalles Bibliográficos
Autores principales:	Venkatakrishnan, Varun, Ghode, Abhijeet, Tulsian, Nikhil K., Anand, Ganesh S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552185/ https://www.ncbi.nlm.nih.gov/pubmed/37808519 http://dx.doi.org/10.3389/fmolb.2023.1202268

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