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Serum PAI-1/BDNF Ratio Is Increased in Alzheimer’s Disease and Correlates with Disease Severity

[Image: see text] We previously demonstrated that serum levels of plasminogen activator inhibitor-1 (PAI-1), which inhibits both the tissue plasminogen activator (tPA) and plasmin activity, are increased in patients with Alzheimer’s disease. tPA/plasmin not only prevents the accumulation of β-amyloi...

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Detalles Bibliográficos
Autores principales:	Angelucci, Francesco, Veverova, Katerina, Katonová, Alžbeta, Vyhnalek, Martin, Hort, Jakub
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552510/ https://www.ncbi.nlm.nih.gov/pubmed/37810633 http://dx.doi.org/10.1021/acsomega.3c04076

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