Functionalized Copper Nanoparticles with Gold Nanoclusters: Part I. Highly Selective Electrosynthesis of Hydrogen Peroxide

[Image: see text] Copper nanoparticles (CuNPs) and gold nanoclusters (AuNCs) show a high catalytic performance in generating hydrogen peroxide (H(2)O(2)), a property that can be exploited to kill disease-causing microbes and to carry carbon-free energy. Some combinations of NPs/NCs can generate synergistic effects to produce stronger antiseptics, such as H(2)O(2) or other reactive oxygen species (ROS). Herein, we demonstrate a novel facile AuNC surface decoration method on the surfaces of CuNPs using galvanic displacement. The Cu–Au bimetallic NPs presented a high selective production of H(2)O(2) via a two-electron (2e(–)) oxygen reduction reaction (ORR). Their physicochemical analyses were conducted by scanning electron microscopy (SEM), transmitting electron microscopy (TEM), X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS). With the optimized Cu–Au(1.5)NPs showing their particle sizes averaged in 53.8 nm, their electrochemical analysis indicated that the pristine AuNC structure exhibited the highest 2e(–) selectivity in ORR, the CuNPs presented the weakest 2e(–) selectivity, and the optimized Cu–Au(1.5)NPs exhibited a high 2e(–) selectivity of 95% for H(2)O(2) production, along with excellent catalytic activity and durability. The optimized Cu–Au(1.5)NPs demonstrated a novel pathway to balance the cost and catalytic performance through the appropriate combination of metal NPs/NCs.