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Widespread and dynamic expression of granzyme C by skin-resident antiviral T cells

After recognition of cognate antigen (Ag), effector CD8(+) T cells secrete serine proteases called granzymes in conjunction with perforin, allowing granzymes to enter and kill target cells. While the roles for some granzymes during antiviral immune responses are well characterized, the function of o...

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Detalles Bibliográficos
Autores principales: Lujan, Ramon A., Pei, Luxin, Shannon, John P., Dábilla, Nathânia, Dolan, Patrick T., Hickman, Heather D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552530/
https://www.ncbi.nlm.nih.gov/pubmed/37809077
http://dx.doi.org/10.3389/fimmu.2023.1236595