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The RNA ligation method using modified splint DNAs significantly improves the efficiency of circular RNA synthesis

Circular RNA (circRNA) is a non-coding RNA with a covalently closed loop structure and usually more stable than messenger RNA (mRNA). However, coding sequences (CDSs) following an internal ribosome entry site (IRES) in circRNAs can be translated, and this property has been recently utilized to produ...

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Detalles Bibliográficos
Autores principales: Kim, Yoon-Seob, Kim, Do-Hyung, An, Daegi, Lim, Younghyun, Seo, Young-Jin, Kim, Hak Kyun, Kang, Ho-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552601/
https://www.ncbi.nlm.nih.gov/pubmed/37808549
http://dx.doi.org/10.1080/19768354.2023.2265165

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