S-acylation of p62 promotes p62 droplet recruitment into autophagosomes in mammalian autophagy

p62 is a well-characterized autophagy receptor that recognizes and sequesters specific cargoes into autophagosomes for degradation. p62 promotes the assembly and removal of ubiquitinated proteins by forming p62-liquid droplets. However, it remains unclear how autophagosomes efficiently sequester p62...

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Detalles Bibliográficos
Autores principales: Huang, Xue, Yao, Jia, Liu, Lu, Chen, Jing, Mei, Ligang, Huangfu, Jingjing, Luo, Dong, Wang, Xinyi, Lin, Changhai, Chen, Xiaorong, Yang, Yi, Ouyang, Sheng, Wei, Fujing, Wang, Zhuolin, Zhang, Shaolin, Xiang, Tingxiu, Neculai, Dante, Sun, Qiming, Kong, Eryan, Tate, Edward W., Yang, Aimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552648/
https://www.ncbi.nlm.nih.gov/pubmed/37802024
http://dx.doi.org/10.1016/j.molcel.2023.09.004

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