Exosomes from PYCR1 knockdown bone marrow mesenchymal stem inhibits aerobic glycolysis and the growth of bladder cancer cells via regulation of the EGFR/PI3K/AKT pathway

Bladder cancer (BC) is a heterogeneous disease, and pyrroline-5-carboxylate reductase 1 (PYCR1) can promote the proliferation and invasion of BC cells and accelerate BC progression. In the present study, si-PYCR1 was loaded into bone marrow mesenchymal stem cell (BMSC)-derived exosomes (Exos) in BC....

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Detalles Bibliográficos
Autores principales: Li, Zhuo, Jiang, Ying, Liu, Jian, Fu, Huifeng, Yang, Quan, Song, Wei, Li, Yuanwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552724/
https://www.ncbi.nlm.nih.gov/pubmed/37293856
http://dx.doi.org/10.3892/ijo.2023.5532

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