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USP35 promotes hepatocellular carcinoma progression by protecting PKM2 from ubiquitination-mediated degradation

Hepatocellular carcinoma (HCC) is the most frequently diagnosed primary liver cancer with a high mortality rate and imposes a huge burden on patients and society. Recently, ubiquitin-specific protease 35 (USP35) was found to be involved in cell proliferation and mitosis, but its role in HCC remains...

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Detalles Bibliográficos
Autores principales: Lv, Tao, Zhang, Bo, Jiang, Chenghao, Zeng, Qiwen, Yang, Jiayin, Zhou, Yongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552738/
https://www.ncbi.nlm.nih.gov/pubmed/37594129
http://dx.doi.org/10.3892/ijo.2023.5561

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