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A genetic variation in fucosyltransferase 8 accelerates HIV-1 disease progression indicating a role for N-glycan fucosylation

OBJECTIVES: Core fucosylation by fucosyltransferase 8 (FUT8) is an important posttranslational modification that impacts components of the immune system. Genetic variations in FUT8 can alter its function and could, therefore, play a role in the antiviral immune response and pathogenesis of HIV-1. Th...

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Detalles Bibliográficos
Autores principales:	van Pul, Lisa, Maurer, Irma, Boeser-Nunnink, Brigitte D.M., Harskamp, Agnes M., van Dort, Karel A., Kootstra, Neeltje A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	Basic Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552802/ https://www.ncbi.nlm.nih.gov/pubmed/37598360 http://dx.doi.org/10.1097/QAD.0000000000003689

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