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USP5 promotes lipopolysaccharide-induced apoptosis and inflammatory response by stabilizing the TXNIP protein

BACKGROUND: The role of thioredoxin-interacting protein (TXNIP) in lipopolysaccharide-induced liver injury in mice has been reported, but the underlying mechanisms are poorly understood. METHODS: We overexpressed deubiquitinase in cells overexpressing TXNIP and then detected the level of TXNIP to sc...

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Detalles Bibliográficos
Autores principales: Shi, Songchang, Pan, Xiaobin, Chen, Minyong, Zhang, Lihui, Zhang, Shujuan, Wang, Xincai, Shi, Songjing, Chen, Zhixin, Lin, Wei, Jiang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10553006/
https://www.ncbi.nlm.nih.gov/pubmed/37534934
http://dx.doi.org/10.1097/HC9.0000000000000193

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