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THU476 Role Of Mitochondrial Sirtuins 3 And 5 On Glutamine Addiction In Prostate Cancer Cell

Disclosure: K.M. Hasan: None. T.C. Friedman: None. W. Chen: None. Myc-transformed and hypoxic cancer cells are sensitive to glutamine deprivation. Reprogramming to glutamine addiction helps to maintain the TCA cycle pool and anaplerosis that provide cancer cells energy and various macromolecules cri...

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Detalles Bibliográficos
Autores principales: Hasan, Kamrul M, Friedman, Theodore C, Chen, Wenyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10553655/
http://dx.doi.org/10.1210/jendso/bvad114.2104