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Human genetic adaptation related to cellular zinc homeostasis
SLC30A9 encodes a ubiquitously zinc transporter (ZnT9) and has been consistently suggested as a candidate for positive selection in humans. However, no direct adaptive molecular phenotype has been demonstrated. Our results provide evidence for directional selection operating in two major complementa...
Autores principales: | Roca-Umbert, Ana, Garcia-Calleja, Jorge, Vogel-González, Marina, Fierro-Villegas, Alejandro, Ill-Raga, Gerard, Herrera-Fernández, Víctor, Bosnjak, Anja, Muntané, Gerard, Gutiérrez, Esteban, Campelo, Felix, Vicente, Rubén, Bosch, Elena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10553801/ https://www.ncbi.nlm.nih.gov/pubmed/37747921 http://dx.doi.org/10.1371/journal.pgen.1010950 |
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