CD8+ cells and small viral reservoirs facilitate post-ART control of SIV replication in M3+ Mauritian cynomolgus macaques initiated on ART two weeks post-infection

Sustainable HIV remission after antiretroviral therapy (ART) withdrawal, or post-treatment control (PTC), remains a top priority for HIV treatment. We observed surprising PTC in an MHC-haplomatched cohort of MHC-M3+ SIVmac239+ Mauritian cynomolgus macaques (MCMs) initiated on ART at two weeks post-i...

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Detalles Bibliográficos
Autores principales: Harwood, Olivia E., Matschke, Lea M., Moriarty, Ryan V., Balgeman, Alexis J., Weaver, Abigail J., Ellis-Connell, Amy L., Weiler, Andrea M., Winchester, Lee C., Fletcher, Courtney V., Friedrich, Thomas C., Keele, Brandon F., O’Connor, David H., Lang, Jessica D., Reynolds, Matthew R., O’Connor, Shelby L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10553806/
https://www.ncbi.nlm.nih.gov/pubmed/37747933
http://dx.doi.org/10.1371/journal.ppat.1011676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10553806/
https://www.ncbi.nlm.nih.gov/pubmed/37747933
http://dx.doi.org/10.1371/journal.ppat.1011676

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