Local negative feedback of Rac activity at the leading edge underlies a pilot pseudopod-like program for amoeboid cell guidance

To migrate efficiently, neutrophils must polarize their cytoskeletal regulators along a single axis of motion. This polarization process is thought to be mediated through local positive feedback that amplifies leading edge signals and global negative feedback that enables sites of positive feedback...

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Detalles Bibliográficos
Autores principales: Town, Jason P., Weiner, Orion D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10553818/
https://www.ncbi.nlm.nih.gov/pubmed/37747905
http://dx.doi.org/10.1371/journal.pbio.3002307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10553818/
https://www.ncbi.nlm.nih.gov/pubmed/37747905
http://dx.doi.org/10.1371/journal.pbio.3002307

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